2009
Cusumano CK, Hultgren SJ.
Bacterial adhesion - A source of alternate antibiotic targets.
IDrugs. 2009 Nov;12(11):699-705.
Waksman G, Hultgren SJ.
Structural biology of the chaperone-usher pathway of pilus biogenesis.
Nature Rev Microbiol. 2009 Nov;7(11):765-74.
Kostakioti M, Hadjifrangiskou M, Pinkner JS, Hultgren SJ.
QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli.
Mol Microbiol. 2009 Sep;73(6):1020-31.
Hung CS, Dodson KW, Hultgren SJ.
A murine model of urinary tract infection.
Nature Protoc. 2009;4(8):1230-43.
Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ.
Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development.
Infect Immun. 2009 Sep;77(9):3626-38.
Czaja CA, Stamm WE, Stapleton AE, Roberts PL, Hawn TR, Scholes D, Samadpour M, Hultgren SJ, Hooton TM.
Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women.
J Infect Dis. 2009 Aug 15;200(4):528-36.
Mysorekar IU, Isaacson-Schmid M, Walker JN, Mills JC, Hultgren SJ.
Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection.
Cell Host Microbe. 2009 May 8;5(5):463-75.
Kline KA, Kau AL, Chen SL, Lim A, Pinkner JS, Rosch J, Nallapareddy SR, Murray BE, Henriques-Normark B, Beatty W, Caparon MG, Hultgren SJ.
Mechanism for sortase localization and role in efficient pilus assembly in Enterococcus faecalis.
J Bacteriol. 2009 Mar 13.
Henderson JP, Crowley JR, Pinkner JS, Walker JN, Tsukayama P, Stamm WE, Hooton TM, Hultgren SJ.
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli.
PLoS Pathog. 2009 Feb;5(2):e1000305.
Hultgren S, Goldstein JM, Delancey JO, Bandstra ES, Brady KT, Brown JS, Deng HW, Dunaif A, Ehrmann DA, Mayer EA, Sinha R, Tobet S, Levine JE.
The vital role of ORWH.
Science. 2009 Feb 20;323(5917):1009-10.
Nenninger AA, Robinson LS, Hultgren SJ.
Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF.
Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):900-5. Epub 2009 Jan 8.
2008
Verger D, Rose RJ, Paci E, Costakes G, Daviter T, Hultgren S, Remaut H, Ashcroft AE, Radford SE, Waksman G.
Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF.
Structure. 2008 Nov 12;16(11):1724-31.
Ingersoll MA, Kline KA, Nielsen HV, Hultgren SJ.
G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity.
Cell Microbiol. 2008 Dec;10(12):2568-78.
Rosen DA, Hung CS, Kline KA, Hultgren SJ.
Streptozocin-induced diabetic mouse model of urinary tract infection.
Infect Immun. 2008 Sep;76(9):4290-8.
Berg V, Das P, Chorell E, Hedenström M, Pinkner JS, Hultgren SJ, Almqvist F.
Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli.
Bioorg Med Chem Lett. 2008 May 7.
Remaut H, Tang C, Henderson NS, Pinkner JS, Wang T, Hultgren SJ, Thanassi DG, Waksman G, Li H.
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.
Cell. 2008 May 16;133(4):640-52.
Rosen DA, Pinkner JS, Walker JN, Elam JS, Jones JM, Hultgren SJ.
Molecular Variations in Klebsiella pneumoniae and Escherichia coli FimH Affect Function and Pathogenesis in the Urinary Tract.
Infect Immun. 2008 May 12.
Wellens A, Garofalo C, Nguyen H, Van Gerven N, Slättegård R, Wyns L, Oscarson S, De Greve H, Hultgren S, Bouckaert J.
Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.
PLoS ONE. 2008 Apr 30;3(4):e2040.
Rosen DA, Pinkner JS, Jones JM, Walker JN, Clegg S, Hultgren SJ.
Utilization of an IBC Pathway in Klebsiella pneumoniae Urinary Tract Infection and the Effects of FimK on Type 1 Pilus Expression.
Infect Immun. 2008 Apr 14.
Hultgren S, Elam J.
Infectious disease and women's health.
Nat Rev Microbiol. 2008 Apr;6(4):254.
Justice SS, Hunstad DA, Cegelski L, Hultgren SJ.
Morphological plasticity as a bacterial survival strategy.
Nat Rev Microbiol. Feb 2008.Rosen DA, Hooton TM, Stamm WE, Humphrey PA, Hultgren SJ.
Detection of intracellular bacterial communities in human urinary tract infection.
PLoS Med. 2007 Dec;4(12):e329.
Cegelski L, Marshall GR, Eldridge GR, Hultgren SJ.
The biology and future prospects of antivirulence therapies.
Nat Rev Microbiol. 2008 Jan;6(1):17-27.Hannan TJ, Mysorekar IU, Chen SL, Walker JN, Jones JM, Pinkner JS, Hultgren SJ, Seed PC.
LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis.
Mol Microbiol. 2008 Jan 7;67(1):116-128.