2003
Lee YM, Almqvist F, Hultgren SJ.
Targeting virulence for antimicrobial chemotherapy.
Curr Opin Pharmacol. 2003 Oct;3(5):513-9.Anderson GG, Palermo JJ, Schilling JD, Roth R, Heuser J, Hultgren SJ.
Intracellular bacterial biofilm-like pods in urinary tract infections.
Science. 2003 Jul 4;301(5629):105-7.Chapman MR, Robinson LS, Hultgren SJ.
Escherichia coli’s How-To Guide for Forming Amyloid.
ASM News 2003. 69:3 pp. 121-126.Larsson A, Ohlsson J, Dodson KW, Hultgren SJ, Nilsson U, Kihlberg J.
Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides.
Bioorg Med Chem. 2003 May 15;11(10):2255-2261.Barnhart MM, Sauer FG, Pinkner JS, Hultgren SJ.
Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly.
J Bacteriol. 2003 May;185(9):2723-30.Schilling JD, Martin SM, Hung CS, Lorenz RG, Hultgren SJ.
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli.
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4203-8. Epub 2003 Mar 24.Emtenas H, Carlsson M, Pinkner JS, Hultgren SJ, Almqvist F.
Stereoselective synthesis of optically active bicyclic beta-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteria.
Org Biomol Chem. 2003 Apr 21;1(8):1308-14.Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG, Hultgren SJ.
CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.
Infect Immun. 2003 Mar;71(3):1470-80.2002
Schilling JD, Lorenz RG, Hultgren SJ.
Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli.
Infect Immun. 2002 Dec;70(12):7042-9.Emtenas H, Ahlin K, Pinkner JS, Hultgren SJ, Almqvist F.
Design and parallel solid-phase synthesis of ring-fused 2-pyridinones that target pilus biogenesis in pathogenic bacteria.
J Comb Chem. 2002 Nov-Dec;4(6):630-9.Sauer FG, Pinkner JS, Waksman G, Hultgren SJ.
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation.
Cell. 2002 Nov 15;111(4):543-51.Thanassi DG, Stathopoulos C, Dodson K, Geiger D, Hultgren SJ.
Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis.
J Bacteriol. 2002 Nov;184(22):6260-9.Jones CH, Dexter P, Evans AK, Liu C, Hultgren SJ, Hruby DE.
Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin.
J Bacteriol. 2002 Oct;184(20):5762-71.Schilling JD, Hultgren SJ, Lorenz RG.
Recent advances in the molecular basis of pathogen recognition and host responses in the urinary tract.
Int Rev Immunol. 2002 Jul-Oct;21(4-5):291-304.Darby C, Hultgren SJ.
Innate defense evicts bacterial squatters.
Nat Immunol. 2002 Jul;3(7):602-4Schilling JD, Hultgren SJ.
Recent advances into the pathogenesis of recurrent urinary tract infections: the bladder as a reservoir for uropathogenic Escherichia coli.
Int J Antimicrob Agents. 2002 Jun;19(6):457-60.Knight SD, Choudhury D, Hultgren S, Pinkner J, Stojanoff V, Thompson A.
Structure of the S pilus periplasmic chaperone SfaE at 2.2 A resolution.
Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1016-22.Hung CS, Bouckaert J, Hung D, Pinkner J, Widberg C, DeFusco A, Auguste CG, Strouse R, Langermann S, Waksman G, Hultgren SJ.
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection.
Mol Microbiol. 2002 May;44(4):903-15.Mysorekar IU, Mulvey MA, Hultgren SJ, Gordon JI.
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli.
J Biol Chem. 2002 Mar 1;277(9):7412-9. Epub 2001 Dec 13.Chapman MR, Robinson LS, Pinkner JS, Roth R, Heuser J, Hammar M, Normark S, Hultgren SJ.
Role of Escherichia coli curli operons in directing amyloid fiber formation.
Science. 2002 Feb 1;295(5556):851-5.Bann JG, Pinkner J, Hultgren SJ, Frieden C.
Real-time and equilibrium (19)F-NMR studies reveal the role of domain-domain interactions in the folding of the chaperone PapD.
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):709-14. Epub 2002 Jan 15.Martinez JJ, Hultgren SJ.
Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli.
Cell Microbiol. 2002 Jan;4(1):19-28.