[Instructions] [Metabolic Reconstruction] [Eukaryotic Pathways]


1. Enzymes in each data set (represented by EC Numbers) are highlighted in the metabolic maps, originally obtained from KEGG.

2. Left clicking inside the highlighted box leads to the KEGG enzyme annotation (Arrow "a").

3. Left clicking the upper left corner of the highlighted box leads to a list of candidate probesets assigned to that specific enzyme (Arrow "b").

Summary Report

Metabolic Reconstruction for UTI89

Lysine biosynthesis
Caprolactam degradation
Taurine and hypotaurine metabolism
Glycerolipid metabolism
Pyruvate metabolism
Inositol phosphate metabolism
Fatty acid biosynthesis (path 1)
Biphenyl degradation
Bile acid biosynthesis
Fatty acid biosynthesis (path 2)
Toluene and xylene degradation
Oxidative phosphorylation
Vitamin B6 metabolism
2,4-Dichlorobenzoate degradation
Glutamate metabolism
Lysine degradation
Tetrachloroethene degradation
ATP synthesis
Alanine and aspartate metabolism
Penicillins and cephalosporins biosynthesis
Nitrobenzene degradation
Tryptophan metabolism
Stilbene, coumarine and lignin biosynthesis
Tetracycline biosynthesis
1,4-Dichlorobenzene degradation
Flavonoid biosynthesis
Aminophosphonate metabolism
Fluorene degradation
Starch and sucrose metabolism
Carbazole degradation
RNA polymerase
Type II secretion system
Glyoxylate and dicarboxylate metabolism
Fatty acid metabolism
1,2-Dichloroethane degradation
Ubiquinone biosynthesis
Synthesis and degradation of ketone bodies
Benzoate degradation via CoA ligation
Nicotinate and nicotinamide metabolism
Glycine, serine and threonine metabolism
Alkaloid biosynthesis I
Selenoamino acid metabolism
N-Glycan biosynthesis
DNA polymerase
N-Glycan degradation
Glycolysis / Gluconeogenesis
Phospholipid degradation
O-Glycan biosynthesis
Propanoate metabolism
3-Chloroacrylic acid degradation
Ethylbenzene degradation
Pantothenate and CoA biosynthesis
Styrene degradation
Methionine metabolism
Arginine and proline metabolism
Cysteine metabolism
Alkaloid biosynthesis II
Cyanoamino acid metabolism
Nucleotide sugars metabolism
Streptomycin biosynthesis
Citrate cycle (TCA cycle)
Prostaglandin and leukotriene metabolism
Biosynthesis of ansamycins
Butanoate metabolism
Polyketide sugar unit biosynthesis
Androgen and estrogen metabolism
Carbon fixation
Biosynthesis of siderophore group nonribosomal peptides
Biotin metabolism
Valine, leucine and isoleucine degradation
Histidine metabolism
Biosynthesis of type II polyketide backbone
Terpenoid biosynthesis
Biosynthesis of type II polyketide products
Phenylalanine, tyrosine and tryptophan biosynthesis
Aminoacyl-tRNA biosynthesis
Novobiocin biosynthesis
Limonene and pinene degradation
D-Glutamine and D-glutamate metabolism
Aminosugars metabolism
Diterpenoid biosynthesis
D-Arginine and D-ornithine metabolism
Glycosaminoglycan degradation
Pentose phosphate pathway
D-Alanine metabolism
Inositol metabolism
C5-Branched dibasic acid metabolism
Reductive carboxylate cycle (CO2 fixation)
Urea cycle and metabolism of amino groups
Folate biosynthesis
Valine, leucine and isoleucine biosynthesis
Tyrosine metabolism
Nitrogen metabolism
1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
beta-Alanine metabolism
Glutathione metabolism
Lipopolysaccharide biosynthesis
Protein export
Pentose and glucuronate interconversions
Glycosphingolipid metabolism
Bacterial chemotaxis
Biosynthesis of steroids
One carbon pool by folate
Blood group glycolipid biosynthesis-neolactoseries
Thiamine metabolism
Globoside metabolism
Purine metabolism
Ganglioside biosynthesis
Porphyrin and chlorophyll metabolism
Phenylalanine metabolism
Sulfur metabolism
gamma-Hexachlorocyclohexane degradation
Benzoate degradation via hydroxylation
Peptidoglycan biosynthesis
Flagellar assembly
Type III secretion system
Fructose and mannose metabolism
Methane metabolism
Galactose metabolism
Riboflavin metabolism
Ascorbate and aldarate metabolism
Pyrimidine metabolism

Eukaryotic Pathways in UTI89

TGF-beta signaling pathway
Wnt signaling pathway
Cytokine-cytokine receptor interaction
Calcium signaling pathway
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Neurodegenerative Disorders
Parkinson's disease
Complement and coagulation cascades
Ubiquitin mediated proteolysis
High-mannose type N-glycan biosynthesis
C21-Steroid hormone metabolism
Retinol metabolism
Amyotrophic lateral sclerosis (ALS)
Phosphatidylinositol signaling system
Toll-like receptor signaling pathway
Biosynthesis of vancomycin group antibiotics
Chondroitin / Heparan sulfate biosynthesis
Huntington's disease
Atrazine degradation
Circadian rhythm
Regulation of actin cytoskeleton
Jak-STAT signaling pathway
Circadian rhythm
Blood group glycolipid biosynthesis-lactoseries
MAPK signaling pathway
Dentatorubropallidoluysian atrophy (DRPLA)
Alzheimer's disease
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Metabolic reconstruction performed on UTI89 genome sequence using MetaView software developed by Jian Xu and based on KEGG metabolic pathway annotations.